First a short intro to werewolf cosmology:
(abridged, and I have no clue if they still use it at all.)
There is Gaia, She is the Mother of all, the Earth, the World. Her sister is Luna, the moon goddess.
But there is also the Triad.
The Wyld is chaos, but it is creative chaos. It is fertility and inspiration, evolution and all kinds of change.
The Weaver is statis, the lack of change, constancy, consistancy.
The Wyrm is destruction, entropy.
The Wyld spins things out of chaos without aim or thought. Some of these things, the Weaver weaves into 'existance', meaning that it will be more than a thought or an illusion. The Wyrm breaks down the things the Weaver has made, and turn them into fresh 'stuff' for the Wyld to shape.
Originally the Triad were simply Forces, without mind.
But somehow, the Weaver attained sentience, and decided to weave the Wyrm into it's nets, that the world could become constant, static, and pleasing to the Weaver.
Bound in the webs of the Weaver however, the Wyrm went mad, fragmented, and these fragments attained a twisted sort of sentience, as well as a desire to destroy all.
The Werewolves are the Warriors of Gaia, Her immune system if you like.
Their main enemies are the minions (knowing or unknowing) of the Wyrm, and any or all of it's aspects. The main 3 aspects are the Defiler Wyrm, which deals in the destruction of morality and decency. It feeds and grows stronger when men beat wives they've sworn to honour and protect, bribe eachother, or rape little children. The Beast of War is the most physical destroyer, it thrives and feeds on acts of violence and destruction, killings and mindless slaughter. Finally there is the Devourer Wyrm, which I suppose you'd sum up as Gluttony, gone horribly wrong. It is the aspect of the Wyrm which always hungers for more, and in the end drives all of the Wyrm's minions to take/use/spend much more than they need. Greed and Megalomania are characteristic trades of those who have come to close to the Devourer Wyrm.
Werewolves are (as a group) animistic, and have pretty good arguments, in that they can call up spirits of various kinds. But the Wyrm has spirit minions too, and they spread it's evil across the world as they can. These spirits, called Banes are perhaps the primary foes of the werewolves.
But often the banes cannot be gotten at, and because the werewolves are fighting a loosing battle, they are often forced into fighting "cleaning up" battles, where they simply oppose the deeds on men that are in league (knowing or not) with the Wyrm, such as huge corporations polluting the enviroment.
If you've been paying attention, you should by now be asking yourself "But what about the Weaver?" Well, the Weaver is (among other things) technologyand science (maybe not the most obvious, but it makes a twisted kind of sense, if you think about it long enough, have a athrocentric enough worldview, and really want it to), but most werewolves either consider it a minor nuisance, or at most the lesser of 2 evils, compared to the Wyrm. Perhaps they are right.
Oh, and mind you, by now you know more of the werewolf cosmology than many werewolves themselves.