The players would have been an issue in any game i think. some were just weird.. like dude we called mumbles.
We played at local comic/card/game store, as it was central to all players, and just one day, dude thats like, 70 years old shows up and "joins" makes his character without consulting us, and just kinda joins in. GM rolled with it, despite the fact guy only spoke in a quiet mumbling. after that we just quietly changed our game time. Others were guys who derailed things to tell this totally awesome story of what happened in another game, while playing, people who didnt like that they couldnt just do whatever they wanted without consequences, and other general flakes and such. All in all, excellent game, and i liked the system! were a few small things i'd change, but in the end wasnt to bad.